Chronic Fatigue Syndrome Test

A blood test screening four possible contributors to persistent fatigue, including Epstein-Barr virus, inflammation, vitamin D and white blood cell counts, taken at a clinic or by a home-visit nurse.

Sample: Blood
Collection: Venous draw at clinic or nurse visit
Results in: 5 days
Biomarkers: 4

Tests for

C-reactive protein (CRP)
Vitamin D
Lymphocytes
Epstein-Barr Virus

Compare Health Test Score Clinic or nurse fatigue panel, above typical pricing

£395.00

Buy now — £395.00

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Test specifications

Provider: Better2Know
Sample type: blood
Collection method: venous draw at clinic or nurse visit
Turnaround time: 5 days
Biomarkers tested: 4
At-home test: No
Doctor reviewed: No
Gender focus: Both

What's tested

4 biomarkers as listed by Better2Know.

Infection & Inflammation

C-reactive protein (CRP)

Vitamins

Vitamin D

White blood cells

Lymphocytes

Epstein-Barr Virus

About this test

This test looks at four possible contributors to ongoing fatigue: Epstein-Barr virus antibodies, C-reactive protein as a marker of inflammation, vitamin D level, and lymphocyte counts, which relate to immune function. It suits people who have felt persistently and unusually tired and want to check some common underlying factors.

You can have the venous blood sample taken at a clinic or arrange for a nurse to visit you at home, and results are typically available within five working days of the sample reaching the lab. At £395, this is well above the typical price for energy and fatigue tests of similar depth that we track, which is the main reason for its low value for money score.

Clinical depth scores reasonably, since four markers is a moderate spread for this category, and clarity scores well thanks to a full biomarker list and stated turnaround. It scores lower on collection convenience, since it needs a clinic visit or booked nurse rather than a postal sample, and on results and follow-up, since doctor review of your result is not confirmed as standard.

Who is it for?

This suits you if you have had persistent, unexplained fatigue and want to check a small group of common contributing factors, such as past Epstein-Barr infection, low vitamin D, inflammation or an immune-system marker, and are comfortable attending a clinic or booking a home nurse visit. It does not diagnose chronic fatigue syndrome or ME, and if your fatigue is severe or getting worse, seeing a GP directly is the more appropriate first step.

If the price is a concern, consider whether a smaller, targeted test would answer your specific question more cheaply, for example a standalone vitamin D check if low vitamin D is your main worry.

How it works

You can have the venous blood sample taken at a Better2Know clinic, or arrange for a nurse to visit you at home, and the sample is sent to the lab for analysis of all four markers. Results are typically available within five working days of the sample reaching the lab, and you will be notified by phone, email or text, with full results in your online patient area. If a problem is identified, Better2Know can arrange a private doctor consultation.

Pros & cons

Pros

Covers four different possible contributors to fatigue in one test
Choice of clinic visit or a nurse who comes to you
Clear published biomarker list and turnaround time

Cons

Costs far more than typical energy and fatigue tests of this depth
Five working days is slower than many single-marker tests
Doesn't confirm a doctor checks your result before you see it

Our editorial score

Compare Health Test Score Clinic or nurse fatigue panel, above typical pricing

Editorial confidence: 9.0/10

This test checks four markers linked to persistent fatigue, including Epstein-Barr virus, an inflammation marker, vitamin D and white blood cell counts, for £395. That is well above the typical price for similarly sized energy and fatigue tests we track, with results taking five working days once the lab has your sample.

Score breakdown

Clarity and documentation 9.0/10

The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.
Clinical depth 5.8/10

4 biomarkers, placing it in the 22nd percentile of energy fatigue tests we track.
Collection convenience 4.0/10

Requires a venous draw at a clinic; a home nurse visit is offered; results in around 5 days, slower than similar tests.
Results and follow-up 3.0/10

Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.
Trust signals 6.5/10

Trustpilot 4.2 from 775 reviews; CQC registered; trading 18+ years.
Value for money 2.0/10

£395.00 against a median of £102.00 for the 8 similarly sized energy fatigue tests we track (+287%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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