Comfort Screen

Screens for eight STIs and related infections from a single urine sample, avoiding the need for a blood draw or swab. Suits people who want broad STI coverage but would rather not give blood, or who have genital discomfort or itching.

Sample
Urine
Collection
Urine sample at clinic or nurse visit
Results in
2 days
Biomarkers
8
Tests for
  • Chlamydia
  • Gonorrhoea
  • Gardnerella
  • Herpes Simplex Type 1
  • Herpes Simplex Type 2
  • Mycoplasma
  • Trichomonas
  • Ureaplasma

Test specifications

Provider
Better2Know
Sample type
urine
Collection method
urine sample at clinic or nurse visit
Turnaround time
2 days
Biomarkers tested
8
At-home test
No
Doctor reviewed
No
Gender focus
Both

What's tested

8 biomarkers as listed by Better2Know.

STI Urine

  • Chlamydia
  • Gonorrhoea
  • Gardnerella
  • Herpes Simplex Type 1
  • Herpes Simplex Type 2
  • Mycoplasma
  • Trichomonas
  • Ureaplasma

About this test

The Comfort Screen tests a single urine sample for eight infections and organisms: chlamydia, gonorrhoea, mycoplasma, ureaplasma, trichomonas, gardnerella, and herpes simplex types 1 and 2. Better2Know positions it for people who want broad STI coverage but are uncomfortable giving blood, or who have genital itching, discharge or discomfort.

There is no direct comparison group listed for this test, but among the sexual health tests we track it is priced about 24% above the typical cost for a similarly sized panel, at £295. It does cover more infections than most tests of its kind, with eight organisms from one sample.

Clinical depth scores very highly, in the 90th percentile of sexual health tests we track, reflecting the breadth of the eight-organism panel. Collection convenience also scores very highly, thanks to a home nurse visit option alongside clinic testing and a quick two-day turnaround. Results and follow-up is the weak point, since results are not reviewed by a doctor as standard, and value for money is only middling given the cost sits above the typical price for tests of this depth.

Who is it for?

This suits you if you want a wide STI check from a single sample and would rather avoid a blood draw or swab, for example if you are anxious about needles, or if you have genital itching, discharge or discomfort you want investigated alongside standard STI screening.

Better2Know's separate £199 Comfort Screen Home Test Kit tests the same eight organisms without requiring a clinic visit, if avoiding one entirely matters more to you than the fastest possible turnaround.

How it works

You provide a urine sample at a Better2Know clinic or during a home nurse visit; no blood draw or swab is needed. The sample is tested for eight infections and organisms including chlamydia, gonorrhoea and both herpes types, with results uploaded to your secure online patient area and a notification by email or SMS within two working days. Better2Know does not state that results are reviewed by a doctor as standard, though a consultation is offered if you test positive.

Pros & cons

Pros

  • Screens for eight infections and organisms from a single urine sample, avoiding blood draws or swabs.
  • In the 90th percentile for clinical depth among the sexual health tests we track.
  • A home nurse visit is offered as an alternative to a clinic visit.
  • Results are uploaded online with an email or SMS notification within two working days.

Cons

  • At £295, it's priced about 24% above the typical cost for a similarly sized sexual health test.
  • Results are not reviewed by a doctor as standard.
  • Better2Know's own £199 home kit tests the same organisms for less, if you don't need a clinic visit.

Our editorial score

Compare Health Test Score Eight-infection urine STI screen, no blood or swab needed
Editorial confidence: 9.0/10

This £295 urine test screens for eight infections including chlamydia, gonorrhoea and both herpes types, without needing a blood or swab sample. It's priced 24% above the £238 median for similarly sized sexual health tests we track, but covers more ground than most. Results are not reviewed by a doctor as standard, though a consultation is offered if you test positive.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 9.9/10

    8 biomarkers, placing it in the 90th percentile of sexual health tests we track.

  • Collection convenience 5.0/10

    A urine sample taken at a clinic; a home nurse visit is offered; results in around 2 days, in line with or faster than similar tests.

  • Results and follow-up 3.0/10

    Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.

  • Trust signals 6.5/10

    Trustpilot 4.2 from 775 reviews; CQC registered; trading 18+ years.

  • Value for money 5.3/10

    £295.00 against a median of £238.00 for the 40 similarly sized sexual health tests we track (+24%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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