Gluten Allergy test

A blood test combining five markers, gluten IgE and IgG antibodies, HLA tissue typing, Tissue Transglutaminase IgA and Immunoglobulin A, for people investigating a possible gluten reaction or coeliac disease alongside a doctor.

Sample
Blood
Collection
Venous draw at clinic or nurse visit
Results in
10 days
Biomarkers
5
Tests for
  • Immunoglobulin A
  • Gluten Antibodies (IgG) (deamidated)
  • Gluten single IgE Allergen
  • HLA Tissue Typing
  • Tissue Transglutaminase IgA ((Coeliac)

Test specifications

Provider
Better2Know
Sample type
blood
Collection method
venous draw at clinic or nurse visit
Turnaround time
10 days
Biomarkers tested
5
At-home test
No
Doctor reviewed
No
Gender focus
Both

What's tested

5 biomarkers as listed by Better2Know.

Immunity

  • Immunoglobulin A
  • Gluten Antibodies (IgG) (deamidated)
  • Gluten single IgE Allergen
  • HLA Tissue Typing
  • Tissue Transglutaminase IgA ((Coeliac)

About this test

This screen combines five distinct markers: IgE and IgG antibodies to gluten, HLA tissue typing, Tissue Transglutaminase IgA, and Immunoglobulin A. Together these look at gluten reactions from several angles, an immediate allergic response, a longer antibody response, a genetic marker associated with coeliac disease, and a check that the IgA test itself is reliable for you, rather than testing a single antibody in isolation.

Within its allergy comparison group, this test measures more distinct marker types than the group's median of two, but far fewer individual items than the large IgE panels sold by providers such as Check My Body Health, which test 40 to 174 separate allergens rather than a small, targeted set of gluten and coeliac markers. At £495 it is also priced above every peer we compare it with in this group, from Check My Body Health's £119 panels up to Medichecks' £281 nut and seed screen.

The scoring reflects that mix: it does well for clinical depth given the range of marker types covered, but poorly for value for money given the far cheaper alternatives in its comparison group. It also scores lower for collection convenience because it needs a clinic or nurse visit and results take around ten days, and it loses marks for results and follow-up because results are not reviewed by a doctor as standard.

Who is it for?

This suits someone specifically investigating a possible gluten reaction or coeliac disease who wants antibody, allergy and genetic markers looked at together, rather than a broad food or environmental allergy screen.

If a wide allergen panel is what you actually want, Check My Body Health's Premium Allergy Test covers 174 allergens for £169.99, and its Food & Environmental Allergy Test covers 117 for £159.99, both far cheaper and broader than this test if gluten specifically is not your only concern.

How it works

A clinician takes a venous blood sample at a clinic or during a paid home nurse visit and sends it to the lab. Results take around ten days and are made available through Better2Know's online patient area. The fact sheet does not show results being reviewed by a doctor as standard.

Pros & cons

Pros

  • Combines five different marker types: gluten IgE and IgG antibodies, HLA tissue typing, Tissue Transglutaminase IgA and Immunoglobulin A.
  • Looks at gluten sensitivity from several angles rather than a single antibody.
  • A home nurse visit is offered instead of a clinic appointment.

Cons

  • At £495, it costs more than every peer in its comparison group, some by several hundred pounds.
  • Tests far fewer individual allergens than the large IgE panels sold by other providers, if breadth is what you need.
  • Results take around ten days, longer than most other tests in this comparison group.
  • No standard doctor review of results.

Our editorial score

Compare Health Test Score Costliest listed test, but its markers differ from peers
Editorial confidence: 9.5/10

This test combines five different markers, including gluten-specific antibodies, HLA tissue typing and Immunoglobulin A, rather than the large multi-allergen panels other providers sell. At £495 it costs more than every peer in its allergy comparison group, and results take around ten days and are not doctor-reviewed as standard.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 8.5/10

    5 biomarkers against a median of 2 across the 19 tests in its comparison group.

  • Collection convenience 4.0/10

    Requires a venous draw at a clinic; a home nurse visit is offered; results in around 10 days, slower than similar tests.

  • Results and follow-up 3.0/10

    Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.

  • Trust signals 6.5/10

    Trustpilot 4.2 from 775 reviews; CQC registered; trading 18+ years.

  • Value for money 2.0/10

    £495.00 against a comparison-group median of £299.00 (+66%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

Compare with similar tests

This test belongs to our Allergy (IgE) test comparison group. See how it stacks up against equivalent tests from other providers.

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