A blood test measuring methylmalonic acid, a marker that rises when vitamin B12 levels are low, used to pick up early or borderline B12 deficiency that standard B12 tests can miss.
1 biomarker as listed by Better2Know.
Methylmalonic acid (MMA) is a substance that builds up in the blood when vitamin B12 levels are too low, even before a standard B12 test shows an abnormal result. This test measures MMA directly, which can be useful if you have symptoms of B12 deficiency, such as fatigue, tingling or memory difficulties, but a routine B12 blood test has come back borderline or unclear.
There is no comparison group recorded for this specific test, but among the similarly sized vitamins and minerals tests we track, its single biomarker places it in the 31st percentile for clinical depth, on the lower side. At £195, it is priced 129% above the £85 median for tests of similar size, a sizeable premium for one marker.
The listing is clear about what is measured and how the process works. It scores lower on collection convenience, since it requires a venous draw with results taking up to 5 working days, and on results and follow-up, since results are not reviewed by a doctor as standard.
This suits people who have had an inconclusive or borderline standard B12 test and want a more sensitive marker to check for an underlying deficiency, particularly if they are vegetarian, vegan, or have a condition affecting B12 absorption.
If you have not yet had a basic B12 test, a standard vitamin panel is likely to be a more logical and cheaper first step, since this test only reports on the single MMA marker rather than your B12 level itself.
A blood sample is taken by venous draw, either at a Better2Know clinic or from a visiting nurse. The sample is sent to the laboratory to measure methylmalonic acid levels in the serum. Results are typically available within 5 working days. The provider does not state that results are reviewed by a doctor as standard.
This test measures a single marker, methylmalonic acid, which rises when vitamin B12 is low and can catch deficiency before standard B12 levels look abnormal. At £195, it costs well above the £85 median for similarly sized vitamins tests we track, with results ready in about 5 working days.
The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.
1 biomarkers, placing it in the 31st percentile of vitamins tests we track.
Requires a venous draw at a clinic; a home nurse visit is offered; results in around 5 days, slower than similar tests.
Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.
Trustpilot 4.2 from 775 reviews; CQC registered; trading 18+ years.
£195.00 against a median of £85.00 for the 73 similarly sized vitamins tests we track (+129%).
Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.
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