Pernicious Anaemia Antibodies

This blood test checks for two antibodies, gastric parietal cell and intrinsic factor antibodies, that are commonly used alongside other investigations for pernicious anaemia. It suits people investigating a possible cause of long-term vitamin B12 deficiency.

  • Doctor reviewed
Sample
Blood
Collection
Venous draw at clinic or nurse home visit
Results in
5 days
Biomarkers
2
Doctor reviewed
Yes
Tests for
  • Gastric parietal cell antibodies
  • Intrinsic factor antibodies

Test specifications

Sample type
blood
Collection method
venous draw at clinic or nurse home visit
Turnaround time
5 days
Biomarkers tested
2
At-home test
No
Doctor reviewed
Yes
Gender focus
Both

What's tested

2 biomarkers as listed by Blue Horizon Medicals.

Autoimmunity

  • Gastric parietal cell antibodies
  • Intrinsic factor antibodies

About this test

This test measures two autoantibodies, gastric parietal cell antibodies and intrinsic factor antibodies, which the provider describes as the two most commonly requested markers when investigating pernicious anaemia, a condition linked to long-term vitamin B12 deficiency. The presence of one or both antibodies is associated with an increased likelihood of having or developing the condition, rather than being a definitive diagnosis on its own.

With two biomarkers it scores reasonably for clinical depth against the vitamins-category tests we track, but it is one of the weaker performers on value: at £135.25 it costs around 59% more than the median for similarly sized tests in this category. Collection requires a venous blood draw at a clinic, with a nurse home visit as an alternative, and results take around five days.

The listing is clear about what the two markers are and how the sample is taken, supporting the clarity score, though it does not describe the report format. A doctor reviews your results, and trust signals reflect Blue Horizon Medicals' 4.2 Trustpilot rating from 395 reviews, UKAS-accredited partner labs, and more than 17 years trading.

Who is it for?

This suits you if a clinician has suggested investigating pernicious anaemia or an unexplained long-term B12 deficiency and you want to check for these two specific antibodies. Because it scores poorly on value for money against similarly sized vitamins-category tests we track, it is worth confirming with your GP first whether this specific antibody testing is the right next step, since a positive or negative result here does not confirm or rule out the condition on its own. See a GP for advice on interpreting your result alongside your wider symptoms and history.

How it works

A sample is taken by venous blood draw, either at a clinic or during a nurse home visit; there is no at-home collection option for this test. The lab tests for gastric parietal cell antibodies and intrinsic factor antibodies, and a doctor reviews your results before your report is issued. Turnaround is typically around five days from when your sample reaches the lab.

Pros & cons

Pros

  • Covers both of the antibodies most commonly requested when investigating pernicious anaemia.
  • Results reviewed by a doctor.
  • A nurse home visit is offered as an alternative to attending a clinic.

Cons

  • Priced around 59% above the median for similarly sized vitamins-category tests we track, one of the pricier options in that group.
  • Requires a venous blood draw at a clinic or during a nurse visit; no finger-prick alternative.
  • A positive or negative result does not confirm or rule out the condition by itself.

Our editorial score

Compare Health Test Score Two-marker pernicious anaemia antibody test, priced high
Editorial confidence: 10.0/10

This test measures gastric parietal cell and intrinsic factor antibodies, the two most commonly requested markers when investigating pernicious anaemia, for £135.25. That is around 59% above the median for similarly sized vitamins-category tests we track, making it one of the pricier options in that group. It requires a venous blood draw rather than an at-home sample, with results in around five days.

Score breakdown

  • Clarity and documentation 8.0/10

    The listing publishes a short description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 8.3/10

    2 biomarkers, placing it in the 64th percentile of vitamins tests we track.

  • Collection convenience 8.0/10

    A blood sample taken at home by a visiting nurse or phlebotomist; with a venous or clinic option as well; a home nurse visit is offered; results in around 5 days, slower than similar tests.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 7.5/10

    Trustpilot 4.2 from 395 reviews; accredited lab (UKAS ISO 15189 partner labs); trading 17+ years.

  • Value for money 3.5/10

    £135.25 against a median of £85.00 for the 83 similarly sized vitamins tests we track (+59%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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