TRT Protocol Change

A focused blood test that checks testosterone, free testosterone, SHBG, prolactin and oestradiol after you've changed your TRT protocol, so your prescriber can see how your hormone levels have responded. Suited to men already on testosterone replacement therapy rather than those wanting a first, broader check.

  • Doctor reviewed
  • Male
Sample
Blood
Collection
Venous draw at clinic or nurse home visit
Results in
1 day
Biomarkers
6
Doctor reviewed
Yes
Tests for
  • Oestradiol
  • Prolactin
  • Testosterone
  • Albumin
  • SHBG
  • Free Testosterone Calculated

Test specifications

Sample type
blood
Collection method
venous draw at clinic or nurse home visit
Turnaround time
1 day
Biomarkers tested
6
At-home test
No
Doctor reviewed
Yes
Gender focus
Male

What's tested

6 biomarkers as listed by Blue Horizon Medicals.

Hormones

  • Oestradiol
  • Prolactin
  • Testosterone

Proteins

  • Albumin
  • SHBG

Testosterone

  • Free Testosterone Calculated

About this test

This test measures five hormones and proteins used to track a testosterone replacement therapy (TRT) protocol: testosterone, free testosterone (calculated), SHBG, prolactin and oestradiol. Testosterone and free testosterone show the amount of hormone available to your body, SHBG affects how much of that testosterone is bound rather than active, prolactin is checked because raised levels can affect hormone balance, and oestradiol is monitored because testosterone can convert to oestrogen during treatment. It's designed as a follow-up test after a dose or protocol change, not a first-time hormone check.

Against the other tests in our male hormone panel comparison group, this one sits in the middle of the price range at £73.25, with 6 biomarkers against a group median of 8. It's more expensive than similarly sized panels from Randox Health, YorkTest and Selph, but it matches the 6-marker count of Medichecks' TRT with Free Testosterone test for £7.75 less.

It scores well for results and follow-up because a doctor reviews the results, and for documentation because the listing sets out the biomarkers, sample type, turnaround and collection options clearly, though it doesn't show what the report itself looks like. It loses marks on collection convenience because there's no at-home option: you need a venous draw at a clinic or a home nurse visit, albeit with results back in a day. Blue Horizon has been trading since 2009 and holds a Trustpilot score of 4.2 from 395 reviews, using UKAS ISO 15189 partner labs.

Who is it for?

This suits men already on testosterone replacement therapy who have just had a protocol or dose change and need a follow-up blood test for their prescriber, rather than men looking for an initial, broader hormone check.

If you want a wider hormone panel to start with, Randox Health's Male Hormone Test (£48, 8 biomarkers) and YorkTest's Male Hormones Test (£55, 8 biomarkers) cover more markers for less money. This test earns its place mainly as a same-day, doctor-reviewed monitoring option once you're already on treatment.

How it works

This is a venous blood test, taken either at a Blue Horizon clinic or by a nurse who visits your home. Once your sample reaches the lab it is tested for testosterone, free testosterone, SHBG, prolactin and oestradiol, with results back within a day. A doctor reviews the results before you receive them.

Pros & cons

Pros

  • Checks five hormones and proteins relevant to a TRT dose or protocol change in one sample.
  • Results are back within a day.
  • A doctor reviews your results before you see them.
  • Matches the 6-marker count of Medichecks' comparable TRT test for £7.75 less.
  • Nurse home visits are offered if you'd rather not attend a clinic.

Cons

  • No at-home finger-prick option; you need a venous draw at a clinic or nurse visit.
  • Covers fewer markers (6) than the 8-marker median across its comparison group.
  • Costs more than Randox Health's and YorkTest's 8-marker male hormone tests.

Our editorial score

Compare Health Test Score Same panel as Medichecks TRT test, £7.75 cheaper
Editorial confidence: 10.0/10

This is a targeted TRT monitoring panel covering testosterone, free testosterone, SHBG, prolactin and oestradiol, priced at £73.25. It matches the biomarker count of Medichecks' TRT with Free Testosterone test but costs £7.75 less, and results are reviewed by a doctor. The main catch is that it needs a venous blood draw at a clinic or via a home nurse visit rather than a simple finger-prick.

Score breakdown

  • Clarity and documentation 8.0/10

    The listing publishes a short description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 7.0/10

    6 biomarkers against a median of 8 across the 15 tests in its comparison group.

  • Collection convenience 10.0/10

    A blood sample taken at home by a visiting nurse or phlebotomist; with a venous or clinic option as well; a home nurse visit is offered; results in around 1 days, well ahead of the mens hormones norm of 2.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 7.5/10

    Trustpilot 4.2 from 395 reviews; accredited lab (UKAS ISO 15189 partner labs); trading 17+ years.

  • Value for money 7.0/10

    £73.25 against a comparison-group median of £79.00 (-7%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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This test belongs to our Male hormone panel comparison group. See how it stacks up against equivalent tests from other providers.

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