This profile measures active B12 alongside total B12, folate and red blood cell markers, giving a fuller picture of B12 status than a total B12 test alone. It suits anyone who wants more context around fatigue or borderline B12 results, particularly vegetarians and vegans.
5 biomarkers as listed by Blue Horizon Medicals.
This profile checks five markers connected to vitamin B12 status: active B12, total B12, serum folate, haemoglobin and mean cell volume (MCV). Measuring active B12 alongside the standard total B12 reading gives a clearer view of how much B12 your body can actually use, rather than relying on a single total figure that can be misleading in borderline cases. Folate and the blood count markers are included because B12 deficiency and folate deficiency can produce similar effects on red blood cells, so checking them together helps distinguish between the two.
Blue Horizon does not place this test in a formal comparison group against other providers, but its five-marker line-up is broader than most vitamin B12 tests we track, which typically test one thing only. That depth is reflected in a strong clinical depth score. Documentation is also thorough: the listing sets out the sample type, the biomarker list and a same-day-to-next-day turnaround, though it does not describe what the report itself looks like.
The overall score is held back mainly by collection convenience, since this test requires a venous blood draw at a clinic or a nurse home visit rather than an at-home finger-prick kit, and by value for money, where the price sits above the median for similarly sized vitamin panels we track. Trust signals reflect Blue Horizon's Trustpilot rating and its UKAS ISO 15189 partner labs; a doctor's review of your results can be added as an opt-in extra at checkout.
This test suits you if you want a more complete picture of B12 status than a basic total B12 check gives, for example if you have had a borderline total B12 result in the past, follow a vegetarian or vegan diet, or have ongoing fatigue that has not been explained. Including folate and blood count markers alongside B12 also helps if you or your GP want to consider related causes of similar symptoms.
It is less suited if you only need a quick, low-cost total B12 check, or if you would rather use an at-home finger-prick kit than book a venous blood draw or nurse visit. If a single B12 marker is enough for your needs, a simpler test would serve you at a lower price.
This is a blood test. You give a venous blood sample, either at a clinic or via a nurse home visit; there is no at-home finger-prick option for this test. The sample is sent to Blue Horizon's laboratory, with results typically ready within a day of the sample being received. A doctor's review of your results can be added as an opt-in extra at checkout; it is not included in the standard price.
This is a five-marker profile that pairs active B12 with total B12, folate and basic blood counts, at £76.25. Because it checks active B12 rather than total B12 alone, it gives more insight into true B12 status, particularly for vegetarians and vegans. The main catch is that it needs a venous blood draw at a clinic or nurse visit, not a finger-prick kit.
The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.
5 biomarkers, placing it in the 79th percentile of vitamins tests we track.
A blood sample taken at home by a visiting nurse or phlebotomist; with a venous or clinic option as well; a home nurse visit is offered; results in around 1 days, well ahead of the vitamins norm of 3.5.
Results are reviewed by a doctor; the provider does not describe the report format.
Trustpilot 4.2 from 395 reviews; accredited lab (UKAS ISO 15189 partner labs); trading 17+ years.
£76.25 against a median of £94.00 for the 28 similarly sized vitamins tests we track (-19%).
Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.
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