Lyme Disease (Borrelia burgdorferi) Antibodies (ELISA) Blood Test

Measures IgG and IgM antibodies to Borrelia burgdorferi, the bacterium behind Lyme disease, to check whether you've likely been exposed. Suited to people who've had a tick bite or spent time in tick habitats.

  • At-home test
  • Doctor reviewed
Sample
Blood
Collection
At-home finger-prick or in-store clinic or home nurse visit or venous draw at clinic
Results in
4 days
Biomarkers
2
Doctor reviewed
Yes
Tests for
  • Borrelia burgdorfei IgG
  • Borrelia burgdorfei IgM

Test specifications

Provider
Medichecks
Sample type
blood
Collection method
at-home finger-prick or in-store clinic or home nurse visit or venous draw at clinic
Turnaround time
4 days
Biomarkers tested
2
At-home test
Yes
Doctor reviewed
Yes
Gender focus
Both

What's tested

2 biomarkers as listed by Medichecks.

Immunity

  • Borrelia burgdorfei IgG
  • Borrelia burgdorfei IgM

About this test

This test measures two antibodies, IgG and IgM, that your immune system produces in response to Borrelia burgdorferi, the bacterium spread by tick bites that causes Lyme disease. IgM tends to appear first after infection and IgG later, so measuring both gives a broader window for detecting a past or recent exposure than a single antibody would.

With only two biomarkers, this sits toward the lower end for biomarker count among the energy and fatigue tests we track, though that reflects its narrow, single-condition focus rather than a broad panel. We don't currently have other Lyme-specific antibody tests in our data to compare it against on price or depth.

The listing is straightforward: Medichecks states the sample type, the antibody markers covered and a turnaround time, though it doesn't describe the report format. It scores well for collection convenience, since you can do a finger-prick sample at home as well as clinic or nurse-visit options, and every result comes with a doctor's comment.

Who is it for?

This test suits people who have spent time in grassy or wooded areas or had a tick bite and want to check whether they have developed antibodies to Borrelia burgdorferi, typically from around two to six weeks after exposure. It's a narrow test covering only two markers, so it isn't a general infection or fatigue screen despite sitting in that category on our site.

If you currently have symptoms such as a rash, fever or joint pain after a tick bite, the provider recommends seeing a GP promptly rather than waiting for a test, since Lyme disease is diagnosed clinically alongside any blood results.

How it works

You can collect a finger-prick blood sample at home, or choose an in-store clinic visit, a home nurse visit, or a venous draw at a clinic. Once the sample reaches the lab it's analysed for Borrelia burgdorferi IgG and IgM antibodies. Medichecks states a turnaround of around four days, and a doctor adds a comment to your results before you see them.

Pros & cons

Pros

  • Can be done with an at-home finger-prick sample as well as clinic options.
  • Tests both IgG and IgM, covering earlier and later stages of antibody response.
  • Doctor's comment included with every result.
  • Turnaround of around four days from sample receipt.

Cons

  • Covers only two markers, so it won't catch other tick-borne infections.
  • No comparable Lyme antibody tests in our data to judge the price against.
  • Provider does not describe what the results report looks like.

Our editorial score

Compare Health Test Score Two-marker Lyme antibody check, at-home option
Editorial confidence: 10.0/10

Two Borrelia burgdorferi antibodies, IgG and IgM, are covered by this £99 at-home test, which can flag whether you've likely been exposed to Lyme disease. It's a narrow, single-purpose panel, and we don't yet have comparable tests to judge whether it's competitively priced.

Score breakdown

  • Clarity and documentation 8.0/10

    The listing publishes a short description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 4.9/10

    2 biomarkers, placing it in the 6th percentile of energy fatigue tests we track.

  • Collection convenience 8.0/10

    A finger-prick sample you take at home; with a venous or clinic option as well; a home nurse visit is offered; results in around 4 days, slower than similar tests.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 9.5/10

    Trustpilot 4.5 from 2,477 reviews; accredited lab (UKAS ISO 15189 partner labs); doctor review as standard; trading 25+ years.

  • Value for money 6.0/10

    £99.00; no comparable tests to benchmark against yet.

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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