Familial Hypercholesterolaemia Risk

A genetic blood test screening 5 genes linked to familial hypercholesterolaemia, an inherited condition causing high cholesterol, with a doctor-reviewed consultation.

  • Doctor reviewed
Sample
Blood
Collection
Venous draw at clinic
Results in
42 days
Biomarkers
5
Doctor reviewed
Yes
Tests for
  • APOE
  • APOB
  • LDLR
  • LDLRAP1
  • PCSK9

Test specifications

Sample type
blood
Collection method
venous draw at clinic
Turnaround time
42 days
Biomarkers tested
5
At-home test
No
Doctor reviewed
Yes
Gender focus
Both

What's tested

5 biomarkers as listed by Randox Health.

Nutrition

  • APOE
  • APOB
  • LDLR
  • LDLRAP1
  • PCSK9

About this test

This test looks for mutations in 5 genes associated with familial hypercholesterolaemia (FH), an inherited condition that causes high cholesterol from birth and can lead to early heart disease if untreated. Genetic testing here is a marker commonly used to assess inherited risk, aimed at people with high cholesterol, a family history of FH, or a personal history of an early heart attack or stroke.

With 5 biomarkers, it scores reasonably well for clinical depth among the heart health tests we track. Its price of £594 is far above the £55 median for similarly sized heart health tests, though that comparison group is mostly made up of standard cholesterol blood panels rather than genetic tests like this one, so it scores poorly on value for money despite testing a different kind of marker.

It scores well for results and follow-up, since results are reviewed by a doctor as part of a consultation, with a genetic counsellor also available. Collection convenience is lower, reflecting the venous draw and roughly 6-week wait.

Who is it for?

This suits people who already have high cholesterol, especially if it has been present since a young age, or who have a family history of FH or a personal history of an early heart attack or stroke. Because this is a genetic test rather than a standard cholesterol panel, it is not directly comparable to cheaper heart health blood tests, and is worth discussing with your GP first given the cost and the implications a positive result could have for family members.

How it works

A blood sample is taken by venous draw at a Randox clinic and analysed for mutations across 5 genes. The provider states it will make contact within 6 weeks to arrange a results consultation with a genetic counsellor, and results are reviewed by a doctor.

Pros & cons

Pros

  • Screens 5 genes linked to familial hypercholesterolaemia
  • Results are reviewed by a doctor as part of a consultation
  • Includes access to a genetic counsellor before testing

Cons

  • Results take around 6 weeks
  • Far more expensive than standard cholesterol blood tests, though it measures something different
  • Requires a venous draw at a clinic

Our editorial score

Compare Health Test Score Genetic FH panel, doctor-reviewed, priced above heart tests
Editorial confidence: 10.0/10

This £594 test screens 5 genes linked to familial hypercholesterolaemia, an inherited high-cholesterol condition, and includes a doctor-reviewed consultation. It is priced far above the £55 median for similarly sized heart health tests we track, though most of those alternatives are standard cholesterol panels rather than genetic tests.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 7.9/10

    5 biomarkers, placing it in the 57th percentile of heart health tests we track.

  • Collection convenience 3.0/10

    Requires a venous draw at a clinic; results in around 42 days, slower than similar tests.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 9.0/10

    Trustpilot 4.6 from 29,705 reviews; accredited lab (UKAS ISO 15189 (Randox Clinical Laboratory Services, lab 9329)); CQC registered.

  • Value for money 2.0/10

    £594.00 against a median of £55.00 for the 29 similarly sized heart health tests we track (+980%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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