This test analyses 14 genes, including BRCA1, BRCA2 and several genes involved in DNA repair such as CHEK2, MLH1, MSH2, MSH6 and PMS2, for mutations linked to a higher inherited risk of prostate cancer. The provider notes that a family history of prostate, breast or ovarian cancer can point to this kind of genetic risk, and is clear that carrying one of these gene changes raises the chance of developing prostate cancer without making it certain.
There is no comparison group set up for this test yet, so we cannot say how its price or depth stacks up against rival hereditary cancer panels. It stands on its own facts: 14 genes, a venous blood sample, and a doctor review built into the results process.
The scorecard reflects a well-documented product: clinical depth is strong, with 14 biomarkers placing it in the 82nd percentile of the cancer screening tests we track, and the listing is clear about the genes covered, the sample type and the turnaround. Results and follow-up score reasonably well because a doctor reviews the results. Collection convenience is the weak point, since it needs a clinic visit and takes around six weeks, and value for money is only middling at £594 with nothing yet to benchmark it against.
Who is it for?
This suits men with a family history of prostate cancer, or of breast or ovarian cancer in the family, who want to understand whether an inherited gene change could be contributing to their risk. Because a mutation does not guarantee you will develop prostate cancer, it works best alongside a conversation with a clinician about what a result would mean for you. If you are unsure whether genetic testing is the right step, the provider offers a paid phone consultation with a genetic counsellor before you commit to a test.
How it works
You give a venous blood sample at a Randox Health clinic. The lab analyses the sample for mutations across the 14 genes covered by the panel, and a doctor reviews the results before you receive them. The provider states results take around six weeks, after which Randox contacts you to arrange a results consultation.
