Better2Know Gut health

Coeliac Disease - Tissue Transglutaminase Test

Checks for tissue transglutaminase (TTA) antibodies, the marker most closely linked to coeliac disease, from a blood sample. Suits adults with bloating, diarrhoea, wind or unexplained weight loss, especially if a close relative has coeliac disease.

Sample
Blood
Collection
Venous draw at clinic or nurse visit; also home kit £69
Results in
2 days
Biomarkers
4
Tests for
  • Bloating
  • Diarrhoea
  • Flatulence or excess wind
  • Unexplained weight loss

Test specifications

Provider
Better2Know
Sample type
blood
Collection method
venous draw at clinic or nurse visit; also home kit £69
Turnaround time
2 days
Biomarkers tested
4
At-home test
No
Doctor reviewed
No
Gender focus
Both

What's tested

4 biomarkers as listed by Better2Know.

  • Bloating
  • Diarrhoea
  • Flatulence or excess wind
  • Unexplained weight loss

About this test

Tissue transglutaminase (TTA) antibodies are produced when the immune system reacts to gluten in people with a genetic predisposition to coeliac disease. This test measures TTA antibodies from a venous blood sample, and Better2Know positions it for people experiencing bloating, diarrhoea, wind or unexplained weight loss, or who have a close relative with coeliac disease.

There is no direct comparison group listed for this exact test, but among the gut health tests we track it sits well above the typical price for a single-antibody screen, at £195 for the clinic version. A home kit version is available for £69, which brings the cost much closer to the market.

The score reflects strong marks for clinical depth and for clarity, since Better2Know publishes a full description, the biomarker detail, the turnaround time and clear collection options. value for money is the weak point, priced well above typical gut health screens of this kind. Results and follow-up also pulls the score down, because results are not reviewed by a doctor as standard, though Better2Know is CQC registered and can arrange a private doctor consultation if you want one.

Who is it for?

This suits you if you have symptoms such as bloating, diarrhoea, excess wind or unexplained weight loss, or if a close relative has been diagnosed with coeliac disease, and you want a single antibody marker checked without booking a GP appointment first. Since results are not doctor-reviewed as standard, it works best if you are comfortable following up a positive or negative result with your own GP, or paying separately for Better2Know's doctor consultation.

If cost is the main concern, the £69 home kit measures the same thing for considerably less than the £195 clinic version, provided you are comfortable posting a sample rather than visiting a clinic.

How it works

You give a venous blood sample at a Better2Know clinic or during a home nurse visit; a home kit version is also available for £69. Once your sample reaches the laboratory, it is tested for tissue transglutaminase antibodies, with results available within two working days. Better2Know does not state that results are reviewed by a doctor as standard, though a private consultation can be arranged if you want to discuss a positive result.

Pros & cons

Pros

  • Targets tissue transglutaminase antibodies, the marker most closely linked to coeliac disease.
  • Results are ready within two working days of your sample reaching the lab.
  • A £69 home kit brings the cost down from the £195 clinic price.
  • Collection is available via a home nurse visit as well as at a clinic.

Cons

  • There's no standard doctor review of your results.
  • At £195, the clinic version costs well above the typical gut health test we track.
  • Better2Know does not state what the results report looks like.

Our editorial score

Compare Health Test Score Two-day coeliac antibody test, cheaper as a home kit
Editorial confidence: 9.0/10

This £195 blood test looks for tissue transglutaminase antibodies, the marker most closely linked to coeliac disease, and turns results around in two working days. It runs above the typical price for similarly sized gut health tests we track, though a £69 home kit brings the cost down considerably. The biggest gap is that results are not reviewed by a doctor as standard.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 9.3/10

    4 biomarkers, placing it in the 80th percentile of gut health tests we track.

  • Collection convenience 10.0/10

    A blood sample taken at home by a visiting nurse or phlebotomist; with a venous or clinic option as well; a home nurse visit is offered; results in around 2 days, well ahead of the gut health norm of 5.

  • Results and follow-up 3.0/10

    Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.

  • Trust signals 6.5/10

    Trustpilot 4.2 from 775 reviews; CQC registered; trading 18+ years.

  • Value for money 3.8/10

    £195.00 against a median of £126.50 for the 8 similarly sized gut health tests we track (+54%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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