Coeliac/Gluten Sensitivity Profile

A blood test measuring IgA and IgG antibodies used to help assess coeliac disease and gluten sensitivity, alongside tissue transglutaminase IgA. Suited to people investigating unexplained gut symptoms possibly linked to gluten.

  • Doctor reviewed
Sample
Blood
Collection
Venous draw at a partner clinic or home visit by a phlebotomist; not available as a finger-prick kit
Results in
2 days
Biomarkers
3
Doctor reviewed
Yes
Tests for
  • Immunoglobulin A
  • Gliadin Antibodies (IgG) (deamidated)
  • Tissue transglutaminase IgA

Test specifications

Sample type
blood
Collection method
venous draw at a partner clinic or home visit by a phlebotomist; not available as a finger-prick kit
Turnaround time
2 days
Biomarkers tested
3
At-home test
No
Doctor reviewed
Yes
Gender focus
Both

What's tested

3 biomarkers as listed by London Medical Laboratory.

Immunity

  • Immunoglobulin A

Immunology

  • Gliadin Antibodies (IgG) (deamidated)
  • Tissue transglutaminase IgA

About this test

This profile measures total Immunoglobulin A, IgG antibodies to deamidated gliadin, and tissue transglutaminase IgA. These antibodies are commonly raised in coeliac disease, where the immune system reacts to gluten, and checking total IgA alongside the specific antibodies helps rule out a false negative in people who are naturally low in IgA. The panel can also flag patterns associated with non-coeliac gluten sensitivity.

Three markers is above the median of 1 across the 11 coeliac tests we track, putting this ahead of several single-marker screens such as Bluecrest Wellness's Coeliac Disease test at £65. At £124, it is also cheaper than the £169 group median, and considerably less than Better2Know's own Coeliac/Gluten Sensitivity Profile, which tests one marker for £295.

The combination of above-median depth and below-median price drives a solid clinical depth and value for money score. Collection convenience is lower than London Medical Laboratory's other tests because this one needs a venous blood draw at a clinic rather than a finger-prick kit, with no at-home option. Trust signals and results and follow-up reflect the same CQC registration and doctor-reviewed report as the rest of the range.

Who is it for?

This suits you if you have ongoing digestive symptoms, such as bloating, diarrhoea or unexplained weight change, and want to check antibody markers associated with coeliac disease or gluten sensitivity before making dietary changes. It's worth doing this while still eating gluten, since antibody levels can drop once gluten is removed from the diet.

If you want a lower-cost initial check, Bluecrest Wellness's Coeliac Disease test covers 1 marker for £65, though with less coverage than the 3 markers here. Any positive or unclear result should be followed up with a GP, since this test does not itself diagnose coeliac disease.

How it works

This test requires a venous blood draw, either at a partner clinic (plus £35) or via a home visit from a phlebotomist (plus £80); it is not available as a finger-prick kit. The lab measures the three antibody markers, and a doctor reviews the results before you receive your report, typically within 2 days.

Pros & cons

Pros

  • Includes total IgA alongside the specific antibodies, helping avoid a false negative in people with naturally low IgA.
  • At £124, it costs less than the £169 median across the coeliac tests we compare it with.
  • Doctor-reviewed report included as standard.

Cons

  • Requires a venous blood draw; there is no finger-prick home option for this test.
  • Cheaper single-marker coeliac screens exist, such as Bluecrest Wellness's test at £65, for less coverage.
  • Home-visit collection adds £80 on top of the £124 test price.

Our editorial score

Compare Health Test Score 3-marker coeliac panel priced below the group median
Editorial confidence: 10.0/10

This profile checks three antibody markers associated with coeliac disease and gluten sensitivity: total IgA, IgG gliadin antibodies and tissue transglutaminase IgA. At £124 it costs less than the £169 median across the coeliac tests we compare it with, including Better2Know's own Coeliac/Gluten Sensitivity Profile at £295. The main limitation is that it requires a venous blood draw rather than a finger-prick sample.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 9.2/10

    3 biomarkers against a median of 1 across the 11 tests in its comparison group.

  • Collection convenience 9.0/10

    A finger-prick sample you take at home; with a venous or clinic option as well; results in around 2 days, well ahead of the gut health norm of 5.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 6.5/10

    No Trustpilot rating on record; CQC registered; doctor review as standard.

  • Value for money 8.4/10

    £124.00 against a comparison-group median of £169.00 (-27%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

Compare with similar tests

This test belongs to our Coeliac test comparison group. See how it stacks up against equivalent tests from other providers.

View all →

Coeliac Disease Blood Test

Broad coeliac panel priced well below rivals

A 4-antibody blood panel used to assess for coeliac disease, covering tissue transglutaminase, endomysial and deamidated gliadin antibodies plus total IgA, for people with ongoing gut symptoms after eating gluten.

  • At-home test
9.4 / 10

Essential IBS Test

Broad symptom screen priced above the coeliac group median

A 4-marker blood and stool panel screening for coeliac antibodies, gut inflammation and H. pylori infection, for people with IBS-type symptoms who want other common causes checked alongside a GP assessment.

  • At-home test
8.3 / 10

Coeliac Blood Test

Market-median price, lighter on markers than some rivals

Checks for antibodies linked to the body's immune response to gluten, plus total IgA, to help assess whether coeliac disease could be a concern. Suits people with symptoms such as bloating or fatigue who still eat gluten.

8.3 / 10