Tests for a coeliac disease marker from a blood sample. Despite the name, Better2Know's own description discusses tissue transglutaminase (TTA) antibody testing rather than a distinct genetic method.
1 biomarker as listed by Better2Know.
This test is named a genetic profile for coeliac disease, but Better2Know's own description mostly discusses testing for tissue transglutaminase (TTA) antibodies rather than detailing a distinct genetic marker, and only one biomarker, 'Coeliac Disease', is listed. Antibody tests like this are commonly used to help assess for coeliac disease in people with symptoms such as bloating, diarrhoea or unexplained weight loss, or a family history of the condition.
Within Better2Know's 'Coeliac test' comparison group, this is by far the most expensive option: £495 against a group median of £169, and £200 more than the next dearest listed test, Better2Know's own Coeliac/Gluten Sensitivity Profile at £295. It tests the same single marker as most of the cheaper options in the group.
The score is held back mainly by value for money and results and follow-up, both scoring poorly, since results are not doctor-reviewed as standard and the price sits far above the group median. Clarity scores well, since Better2Know publishes a full description, the biomarker, turnaround and collection details, even if the description does not match the 'genetic profile' name particularly closely.
This is hard to recommend on the data alone: Better2Know's own Coeliac/Gluten Sensitivity Profile tests the same single marker for £200 less, and cheaper alternatives such as Selph's Coeliac Disease Blood Test (£63, 4 markers) or Medichecks' Coeliac Blood Test (£169, 2 markers) test more markers for a fraction of the price.
It may still make sense if you specifically want to test with Better2Know and are not focused on cost, but if you were expecting a specific genetic or DNA-based method based on the test's name, it's worth confirming directly with Better2Know what the test actually includes before you book.
You give a venous blood sample at a Better2Know clinic, with a home nurse visit also offered. Once the sample reaches Better2Know's laboratory, it is tested for the coeliac disease marker described in the listing. Results are available within around 10 working days, and Better2Know does not state that they are reviewed by a doctor as standard, though a private consultation can be arranged if the result is positive.
At £495, this is the most expensive test in Better2Know's coeliac comparison group, £200 above the next dearest option and almost triple the group's £169 median. Despite being named a genetic profile, Better2Know's own description focuses on tissue transglutaminase antibody testing rather than a distinct genetic marker. Results take around 10 working days and are not reviewed by a doctor as standard.
The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.
1 biomarkers against a median of 1 across the 11 tests in its comparison group.
Requires a venous draw at a clinic; a home nurse visit is offered; results in around 10 days, slower than similar tests.
Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.
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£495.00 against a comparison-group median of £169.00 (+193%).
Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.
This test belongs to our Coeliac test comparison group. See how it stacks up against equivalent tests from other providers.
Broad coeliac panel priced well below rivals
A 4-antibody blood panel used to assess for coeliac disease, covering tissue transglutaminase, endomysial and deamidated gliadin antibodies plus total IgA, for people with ongoing gut symptoms after eating gluten.
3-marker coeliac panel priced below the group median
A blood test measuring IgA and IgG antibodies used to help assess coeliac disease and gluten sensitivity, alongside tissue transglutaminase IgA. Suited to people investigating unexplained gut symptoms possibly linked to gluten.
Broad symptom screen priced above the coeliac group median
A 4-marker blood and stool panel screening for coeliac antibodies, gut inflammation and H. pylori infection, for people with IBS-type symptoms who want other common causes checked alongside a GP assessment.
Market-median price, lighter on markers than some rivals
Checks for antibodies linked to the body's immune response to gluten, plus total IgA, to help assess whether coeliac disease could be a concern. Suits people with symptoms such as bloating or fatigue who still eat gluten.
Mid-priced coeliac check, cheaper than most rivals
This blood test measures tTg-IgA, the antibody most often used to investigate coeliac disease, to help you decide whether further testing is worthwhile. It suits adults eating a normal, gluten-containing diet who want a first coeliac check.
Cheapest coeliac screen in the comparison group
A rapid at-home finger-prick blood test for tTG-IgA antibodies, a marker commonly used to help assess whether ongoing gluten-related symptoms warrant further investigation.
One of the cheapest coeliac screening tests we compare
A blood test that measures tissue transglutaminase antibodies (tTG), used to screen for coeliac disease, an autoimmune reaction to gluten. It suits people with digestive symptoms who want an initial screen before seeing a GP.
Most biomarkers in its group, but the priciest by far
A blood test combining genetic risk scores and autoantibody screening for both Type 1 diabetes and coeliac disease, for anyone wanting to check both conditions together.
Fastest Better2Know coeliac screen, priced above most peers
Screens for coeliac disease and gluten sensitivity from a single blood marker, with results back in two working days. Suits people who want a faster result than Better2Know's other coeliac screens.
Most expensive test in its coeliac comparison group
A single-marker blood screen for coeliac disease from Better2Know, with results in around 10 working days. Suits people who want a basic check without paying for a wider panel.
Broad coeliac panel priced well below rivals
A 4-antibody blood panel used to assess for coeliac disease, covering tissue transglutaminase, endomysial and deamidated gliadin antibodies plus total IgA, for people with ongoing gut symptoms after eating gluten.
3-marker coeliac panel priced below the group median
A blood test measuring IgA and IgG antibodies used to help assess coeliac disease and gluten sensitivity, alongside tissue transglutaminase IgA. Suited to people investigating unexplained gut symptoms possibly linked to gluten.
Broad symptom screen priced above the coeliac group median
A 4-marker blood and stool panel screening for coeliac antibodies, gut inflammation and H. pylori infection, for people with IBS-type symptoms who want other common causes checked alongside a GP assessment.
Market-median price, lighter on markers than some rivals
Checks for antibodies linked to the body's immune response to gluten, plus total IgA, to help assess whether coeliac disease could be a concern. Suits people with symptoms such as bloating or fatigue who still eat gluten.
