Blue Horizon Medicals Inflammation & autoimmunity

Extractable Nuclear Antibodies (ENA)

This blood test screens for seven extractable nuclear antibodies (ENA), typically requested after a positive antinuclear antibody (ANA) test or when an autoimmune disorder is suspected. It suits people who need this more detailed panel to follow up on that earlier result.

  • Doctor reviewed
Sample
Blood
Collection
Venous draw at clinic or nurse home visit
Results in
6 days
Biomarkers
7
Doctor reviewed
Yes
Tests for
  • anti-CENP
  • anti-Jo-1
  • anti-RNP
  • antiScl-70
  • anti-Sm
  • anti-SS-La
  • anti-SS-Ro

Test specifications

Provider
Blue Horizon Medicals
Sample type
blood
Collection method
venous draw at clinic or nurse home visit
Turnaround time
6 days
Biomarkers tested
7
At-home test
No
Doctor reviewed
Yes
Gender focus
Both

What's tested

7 biomarkers as listed by Blue Horizon Medicals.

  • anti-CENP
  • anti-Jo-1
  • anti-RNP
  • antiScl-70
  • anti-Sm
  • anti-SS-La
  • anti-SS-Ro

About this test

Extractable nuclear antibodies (ENA) are a group of autoantibodies, including anti-RNP, anti-Sm, anti-SS-Ro, anti-SS-La, anti-Jo-1, anti-Scl-70 and anti-CENP, that are often tested together as a panel. The provider notes this test is usually requested following a positive antinuclear antibody (ANA) test, or where there is high suspicion of an autoimmune disorder, so it tends to be a second-line test rather than a first check.

There is no comparison group recorded for this exact panel, so we cannot line it up against named competitors. Against the wider set of inflammation and autoimmunity tests we track, £90.25 sits well below the £149 median for similarly sized panels, and its seven markers place it in the top percentile for clinical depth in that category.

The score is strongest on clinical depth, thanks to the full seven-antibody panel, and on value for money given the price against the category median. It is held back most by collection convenience, since it requires a venous draw at a clinic or a home nurse visit rather than a simpler sample method, and it scores well on results and follow-up because a doctor reviews the results.

Who is it for?

This suits you if a GP or specialist has already run an ANA test and suggested a follow-up ENA panel, or if you have symptoms consistent with a connective tissue disorder and want the fuller seven-antibody breakdown privately. It is not designed as a first screening test for autoimmune symptoms, and because we hold no named peer data for this panel, we cannot tell you whether another provider offers the same seven markers for less.

How it works

The sample is taken as a venous blood draw, either at a clinic or via a nurse who visits your home. The lab tests for seven extractable nuclear antibodies, and results are typically ready in around 6 days. A doctor reviews the results before you receive them.

Pros & cons

Pros

  • Covers all seven common ENA markers in one panel
  • Scores in the top percentile for clinical depth among inflammation tests we track
  • Home nurse visit available if you cannot get to a clinic
  • Doctor reviews your results before you see them

Cons

  • Requires a venous blood draw rather than a simpler finger-prick or stool sample
  • No comparison group listed for this exact panel, so we can't verify it against named competitors
  • Best suited as a follow-up test rather than an initial screen, so it may not be the right first step

Our editorial score

Compare Health Test Score Broad 7-marker autoimmune antibody panel
Editorial confidence: 10.0/10

This is a seven-marker ENA panel priced at £90.25, typically used as a follow-up after a positive ANA test. We have no named competitor data for this exact panel, but it scores highly for clinical depth among the inflammation and autoimmunity tests we track. The main trade-off is collection, since it needs a venous blood draw rather than a finger-prick or stool kit.

Score breakdown

  • Clarity and documentation 8.0/10

    The listing publishes a short description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 10.0/10

    7 biomarkers, placing it in the 95th percentile of inflammation tests we track.

  • Collection convenience 8.0/10

    A blood sample taken at home by a visiting nurse or phlebotomist; with a venous or clinic option as well; a home nurse visit is offered; results in around 6 days, slower than similar tests.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 7.5/10

    Trustpilot 4.2 from 395 reviews; accredited lab (UKAS ISO 15189 partner labs); trading 17+ years.

  • Value for money 8.5/10

    £90.25 against a median of £149.00 for the 9 similarly sized inflammation tests we track (-39%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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