Vitamin B12 Active

Checks active B12 (holotranscobalamin), the form of vitamin B12 taken up and used by your cells, from an at-home sample. Suited to a quick, flexible check on B12 status, including for vegetarians and vegans, who are more at risk of low B12.

  • At-home test
  • Doctor reviewed
Sample
Blood
Collection
At-home finger-prick or Tasso autodraw or venous draw at clinic or nurse home visit
Results in
1 day
Biomarkers
1
Doctor reviewed
Yes
Tests for
  • Vitamin B12 - active

Test specifications

Sample type
blood
Collection method
at-home finger-prick or Tasso autodraw or venous draw at clinic or nurse home visit
Turnaround time
1 day
Biomarkers tested
1
At-home test
Yes
Doctor reviewed
Yes
Gender focus
Both

What's tested

1 biomarker as listed by Blue Horizon Medicals.

Vitamins

  • Vitamin B12 - active

About this test

This test measures active B12 (holotranscobalamin), the fraction of circulating B12 that your cells can actually take up and use, typically 10-30% of total B12. It's commonly used to assess B12 status, including in people following vegetarian or vegan diets, who get less B12 from food and are more likely to run low.

Within the Vitamin B12 test group we track, this one is priced close to the median: £45.25 against £46.00, a difference of about 2%. Medichecks and London Medical Laboratory offer the same single marker for £39, so it isn't the cheapest option, but it beats Randox Health (£46), Forth (£50), Better2Know (£55 and £170) and Bluecrest Wellness (£65) on price, while matching them on the single B12 marker tested.

It scores at the top of the scale for collection convenience, since you can use an at-home finger-prick kit or a Tasso autodraw device as well as a clinic or nurse visit, with results back within a day. It also scores well for results and follow-up, since a doctor reviews the result, and for documentation, since the biomarker, sample type, turnaround and collection options are all published clearly. Blue Horizon has traded since 2009, holds a Trustpilot score of 4.2 from 395 reviews, and uses UKAS ISO 15189 partner labs.

Who is it for?

This suits anyone who wants a quick, doctor-reviewed check on active B12 with a choice of at-home or clinic collection, including vegetarians, vegans, or anyone wondering if fatigue could be linked to low B12.

If price is the only factor, Medichecks and London Medical Laboratory both offer the same single B12 marker for £39, £6.25 less. If you'd rather have a wider panel that includes B12 alongside other B vitamins, Blue Horizon's own Vitamin B Profile covers six B vitamins, though at a considerably higher price.

How it works

You can collect your own sample at home with a finger-prick kit or a Tasso autodraw device, or have a venous draw at a clinic or by a home nurse visit. The sample is tested for active B12, with results back within a day, and a doctor reviews the result before you receive it.

Pros & cons

Pros

  • Can be collected at home with a finger-prick kit or a Tasso autodraw device.
  • Results are back within a day.
  • A doctor reviews your result.
  • Tests active B12 specifically, the fraction your cells can actually use.

Cons

  • Medichecks and London Medical Laboratory test the same marker for £39, £6.25 less.
  • Only tests one marker, so it won't cover other vitamins or minerals.

Our editorial score

Compare Health Test Score Fast at-home B12 test, near the median price for its group
Editorial confidence: 10.0/10

This at-home Active B12 test costs £45.25, close to the £46.00 median for the Vitamin B12 tests we track. It offers the fastest, most flexible collection in that group, at-home finger-prick, Tasso autodraw or a venous option, with results back within a day. Medichecks and London Medical Laboratory offer the same single marker for £39, so it isn't the cheapest, but the collection choice and one-day turnaround set it apart.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 7.5/10

    A single-marker test measuring exactly what it sets out to; depth is not the point of this comparison group.

  • Collection convenience 10.0/10

    A finger-prick sample you take at home; with a venous or clinic option as well; a home nurse visit is offered; results in around 1 days, well ahead of the vitamins norm of 3.5.

  • Results and follow-up 7.0/10

    Results are reviewed by a doctor; the provider does not describe the report format.

  • Trust signals 7.5/10

    Trustpilot 4.2 from 395 reviews; accredited lab (UKAS ISO 15189 partner labs); trading 17+ years.

  • Value for money 6.6/10

    £45.25 against a comparison-group median of £46.00 (-2%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

Compare with similar tests

This test belongs to our Vitamin B12 test comparison group. See how it stacks up against equivalent tests from other providers.

View all →

Vitamin B12 (Active) Blood Test

Tied for cheapest single B12 test, with fast results

This test measures active vitamin B12 on its own, the form of B12 that is actually available for your body to use. It suits people with possible deficiency symptoms, such as fatigue, low energy or memory problems, or a diet or condition that raises their risk.

  • At-home test
8.1 / 10

Vitamin B12 Total

Flexible collection, price close to the group average

This blood test measures total vitamin B12, the standard marker for checking B12 status. It suits people who want a straightforward single-marker check rather than the added detail of active B12 or related markers.

  • At-home test
7.9 / 10