Randox Health Genetic & DNA

Genetic Haemochromatosis Home Test

A saliva-based DNA test for three HFE gene variants (C282Y, H63D, S65C) linked to genetic haemochromatosis, for people with a family history of the condition or iron overload symptoms.

  • At-home test
Sample
Saliva
Collection
At-home saliva sample, posted to lab
Results in
7–14 days
Biomarkers
3
Tests for
  • C282Y
  • H63D
  • S65C

Test specifications

Provider
Randox Health
Sample type
saliva
Collection method
at-home saliva sample, posted to lab
Turnaround time
7–14 days
Biomarkers tested
3
At-home test
Yes
Doctor reviewed
No
Gender focus
Both

What's tested

3 biomarkers as listed by Randox Health.

  • C282Y
  • H63D
  • S65C

About this test

The Genetic Haemochromatosis Home Test analyses a saliva sample for three variants in the HFE gene: C282Y, H63D and S65C. These variants are commonly used to assess genetic predisposition to haemochromatosis, a condition where the body absorbs too much iron; carrying a variant indicates increased risk rather than a diagnosis, and the provider suggests discussing a family history or relevant symptoms with a GP.

With three biomarkers, this sits in the lower range for clinical depth among the genetic and DNA tests we track, since it targets a specific, narrow set of known variants rather than a broad panel. There are no comparable tests currently in our data to benchmark this price against, so the score here reflects the absence of a like-for-like comparison rather than a judgement on the price itself.

The listing scores well for clarity and documentation, setting out the specific variants tested, sample type, collection method and turnaround clearly, though it does not describe what the results report looks like. Results and follow-up scores low because results are not reviewed by a doctor as standard, while trust signals score highly on Randox Health's Trustpilot rating of 4.6 from 29,705 reviews, its UKAS ISO 15189 accredited lab and CQC registration.

Who is it for?

This may suit you if you have a family history of haemochromatosis or iron overload and want to check your genetic risk from home using a saliva sample rather than a blood draw. Randox Health also offers an in-clinic Haemochromatosis Risk test checking the same three HFE variants for the same £84 price, which may suit you better if you would rather have a blood sample taken at a clinic.

There are no other comparable genetic haemochromatosis tests in our data to weigh this against on price or depth.

How it works

You provide a saliva sample at home using the kit provided and post it to the lab, where it is analysed for the C282Y, H63D and S65C variants in the HFE gene. Results are provided within 1 to 2 weeks of the sample arriving at the lab and are not reviewed by a doctor as standard.

Pros & cons

Pros

  • Saliva sample means no blood draw or clinic visit needed.
  • Tests all three HFE variants most commonly linked to haemochromatosis risk.
  • Listing clearly states the exact HFE variants tested and the turnaround time.

Cons

  • No standard doctor review of your results.
  • No comparable tests currently in our data to judge the £84 price against.
  • Tests a narrow set of known variants rather than a broader iron health panel.

Our editorial score

Compare Health Test Score At-home saliva test for haemochromatosis gene risk
Editorial confidence: 9.0/10

Checking for three variants in the HFE gene (C282Y, H63D and S65C), this saliva test assesses genetic predisposition to haemochromatosis, an inherited condition linked to iron overload. At £84 there are currently no directly comparable tests in our data to benchmark the price against, and results take 1 to 2 weeks. It is not reviewed by a doctor as standard.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 5.3/10

    3 biomarkers, placing it in the 13th percentile of genetic dna tests we track.

  • Collection convenience 8.0/10

    A saliva sample you take at home, no needle; results in around 14 days, in line with or faster than similar tests.

  • Results and follow-up 3.0/10

    Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.

  • Trust signals 9.0/10

    Trustpilot 4.6 from 29,705 reviews; accredited lab (UKAS ISO 15189 (Randox Clinical Laboratory Services, lab 9329)); CQC registered.

  • Value for money 6.0/10

    £84.00; no comparable tests to benchmark against yet.

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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