A cheek-swab DNA test covering 110 genes across methylation, nutrition, fitness, sleep, stress and skin. Suits people wanting Stride's fullest standalone DNA panel without the supplement bundle.
60 biomarkers as listed by Stride, of 110 in total.
This test analyses 110 genes spanning core methylation cycles (including MTHFR, COMT and MTR), nutrition and metabolism genes (including APOE, FTO and TCF7L2), plus additional genes covering fitness, sleep, stress and skin that are not detailed individually in the biomarker list. The sample is an at-home cheek swab posted to the lab.
Within Stride's own DNA and methylation range, this is the deepest standalone option: it covers more genes than the Core test (19 genes, £109.85) and Advanced test (52 genes, £174.85), and matches the 110-gene count of the Methylation Stack (£278.85), which bundles the same panel with a supplement. Against the wider comparison group, its 110 genes are well above the group median of 81, though at £207.35 it costs 9% more than the £191.10 group median price.
It scores near the top for clinical depth and for clarity and documentation, since Stride publishes the full gene list, sample type, turnaround and a description of the genetic report. Collection convenience is strong given the simple swab and roughly 10-day turnaround. Value for money is middling, reflecting the above-median price. Results and follow-up score reasonably, helped by the included consultation and a described report format, though results are still not doctor-reviewed.
This suits people who want Stride's fullest gene panel covering methylation, nutrition, fitness, sleep, stress and skin, but do not want to commit to the Methylation Stack's bundled supplement. It is a step up in both depth and price from the Core and Advanced tests.
If budget is tighter, the Core test covers the core methylation cycles for £109.85, or the Advanced test adds nutrition genes for £174.85. If you also want an ongoing methylated B-vitamin supplement, the Methylation Stack covers the same 110 genes plus three months of MS-01 for £278.85.
You collect a sample yourself using an at-home cheek swab and post it to the lab; Stride states results are returned in around 10 working days as a genetic report. A one-to-one consultation is included in the price, though results are not reviewed by a doctor.
The Optimal DNA & Methylation Test reads 110 genes covering methylation, nutrition, fitness, sleep, stress and skin from a cheek swab, with results in 10 working days. At £207.35 it costs 9% more than the £191.10 group median, but matches the gene count of Stride's pricier Methylation Stack (£278.85) without the bundled supplement. Results are not reviewed by a doctor.
The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type, what the report contains.
110 biomarkers against a median of 81 across the 4 tests in its comparison group.
A swab sample you take at home, no needle; results in around 10 days, in line with or faster than similar tests.
A one-to-one consultation is included in the price, though results are not doctor-reviewed; genetic-report report.
Trustpilot 4.7 from 148 reviews; accredited lab (UKAS accredited labs); trading 22+ years.
£207.35 against a comparison-group median of £191.10 (+9%).
Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.
This test belongs to our DNA and methylation test comparison group. See how it stacks up against equivalent tests from other providers.
Priciest of Stride's DNA and methylation panels
A bundle combining Stride's 110-gene Optimal DNA & Methylation test with three months' supply of its methylated B-vitamin supplement. Suits people who want the deepest methylation panel plus an ongoing supplement in one purchase.
Middle of Stride's three DNA tiers on price and gene count
A cheek-swab DNA test analysing 52 genes across methylation and nutrient metabolism, showing how your body processes folate, B vitamins and dietary fat. Suited to people wanting more than a basic methylation panel without paying for the full 110-gene version.
Cheapest of Stride's DNA and methylation panels
A cheek-swab DNA test covering 19 genes across the five core methylation cycles, showing how efficiently your body processes folate and other B vitamins. Suits people wanting an entry-level look at methylation genetics.
Priciest of Stride's DNA and methylation panels
A bundle combining Stride's 110-gene Optimal DNA & Methylation test with three months' supply of its methylated B-vitamin supplement. Suits people who want the deepest methylation panel plus an ongoing supplement in one purchase.
Middle of Stride's three DNA tiers on price and gene count
A cheek-swab DNA test analysing 52 genes across methylation and nutrient metabolism, showing how your body processes folate, B vitamins and dietary fat. Suited to people wanting more than a basic methylation panel without paying for the full 110-gene version.
Cheapest of Stride's DNA and methylation panels
A cheek-swab DNA test covering 19 genes across the five core methylation cycles, showing how efficiently your body processes folate and other B vitamins. Suits people wanting an entry-level look at methylation genetics.
