Core DNA & Methylation Test

All five methylation cycles. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
Sample
Swab
Collection
At-home cheek swab, posted to the lab
Results in
10 days
Biomarkers
19
Doctor reviewed
No
Tests for
  • ADNOS3
  • BHMT
  • CBS (C699T)
  • COMT
  • DHFR
  • FUT2
  • GSS
  • MAOA
  • MAOB
  • MTHFD1
  • MTHFR (A1298C)
  • MTHFR (C677T)
  • +6 more

Test specifications

Provider
Stride
Sample type
swab
Collection method
at-home cheek swab, posted to the lab
Turnaround time
10 days
Biomarkers tested
19
At-home test
Yes
Doctor reviewed
No
Gender focus
Both

What's tested

18 biomarkers as listed by Stride, of 19 in total.

Methylation

  • ADNOS3
  • BHMT
  • CBS (C699T)
  • COMT
  • DHFR
  • FUT2
  • GSS
  • MAOA
  • MAOB
  • MTHFD1
  • MTHFR (A1298C)
  • MTHFR (C677T)
  • MTR
  • MTRR
  • PEMT
  • SOD2ORA2A
  • TCN2
  • VDR

About this test

Core - 19 Genes: All five methylation cycles.

The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT. Choose from three levels, then compare what each one covers below.

  • 1:1 expert consultation included with every level
  • Simple at-home cheek swab, results in 10 working days
  • Analysed at accredited specialist laboratories

Every level reads your core methylation pathways - including MTHFR and COMT - and includes a 1:1 expert consultation. Each step up widens the picture: Advanced adds nutrition and metabolism, Optimal adds fitness, sleep, stress and skin.

Description provided by Stride.

Our editorial score

Compare Health Test Score
Editorial confidence: 10.0/10

Score breakdown

  • Clarity and UX 8.0/10

    The listing publishes a detailed description, some of the biomarkers by name, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical Depth 6.0/10

    19 biomarkers against a median of 81 across the 4 tests in its comparison group.

  • Collection Convenience 6.0/10

    Can be done at home; results in around 10 days.

  • Price Value 9.5/10

    £109.85 against a comparison-group median of £191.10 (-43%).

  • Results and Follow-up 3.0/10

    Results are not doctor-reviewed as standard.

  • Trust Signals 7.5/10

    Trustpilot 4.7 from 148 reviews; accredited lab (UKAS accredited labs); trading 22+ years.

Compare with similar tests

This test belongs to our DNA and methylation test comparison group. See how it stacks up against equivalent tests from other providers.

View all →

Optimal DNA & Methylation Test

Methylation and nutrition in full, plus sleep, stress, skin and fitness. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
7.5 / 10 Best for broad methylation genetics

Methylation Stack

Optimal DNA & methylation test including 46 reports, plus 3 months' supply of MS-01, our methylated B vitamin complex. Unlock your methylation blueprint + daily support.

  • At-home test
7.0 / 10 Best for testing plus support bundle

Advanced DNA & Methylation Test

The five cycles in full, plus 24 reports on how you process food. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
7.0 / 10