A cheek-swab DNA test covering 19 genes across the five core methylation cycles, showing how efficiently your body processes folate and other B vitamins. Suits people wanting an entry-level look at methylation genetics.
18 biomarkers as listed by Stride, of 19 in total.
This test analyses 19 genes covering the five core methylation cycles, including MTHFR, COMT, MTR and MTRR. These genes are commonly used to assess how efficiently your body methylates and processes nutrients such as folate and other B vitamins. The sample is an at-home cheek swab posted to the lab.
Within Stride's own range it is the entry point: the Advanced test covers 52 genes for £174.85, and the Optimal test and Methylation Stack both cover 110 genes for £207.35 and £278.85 respectively. Against the wider comparison group of DNA and methylation tests, its 19 genes are well below the group median of 81, which shows up as a middling clinical depth score, but at £109.85 it is comfortably the cheapest option, 43% below the £191.10 group median.
It scores strongly for value for money given that price gap, and well for collection convenience thanks to the simple swab and roughly 10-day turnaround. Clarity and documentation score well too, since Stride names most of the genes covered, though not the full list found in the higher tiers. It scores lower for results and follow-up: a consultation is included, but results are not doctor-reviewed and the report format is not described.
This is a sensible starting point if you want a first look at your methylation genetics without paying for the wider gene panels. It covers the same core methylation cycles that run through all of Stride's DNA and methylation tests, just without the added nutrition, fitness, sleep, stress and skin genes.
If you want the nutrition genes as well, the Advanced DNA & Methylation Test adds those for £174.85. For the fullest panel, the Optimal DNA & Methylation Test and Methylation Stack both cover 110 genes for £207.35 and £278.85.
You collect a sample yourself using an at-home cheek swab and post it to the lab; no blood or finger-prick is needed. Stride states results are returned in around 10 working days. A one-to-one consultation is included in the price, though the sheet does not describe how results are presented, and results are not reviewed by a doctor.
The Core DNA & Methylation Test reads 19 genes across the five methylation cycles from a cheek swab, with results in 10 working days. At £109.85 it is the cheapest of Stride's DNA and methylation panels, well below the £191.10 group median, though it covers far fewer genes than the Advanced, Optimal and Methylation Stack versions.
The listing publishes a detailed description, some of the biomarkers by name, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.
19 biomarkers against a median of 81 across the 4 tests in its comparison group.
A swab sample you take at home, no needle; results in around 10 days, in line with or faster than similar tests.
A one-to-one consultation is included in the price, though results are not doctor-reviewed; the provider does not describe the report format.
Trustpilot 4.7 from 148 reviews; accredited lab (UKAS accredited labs); trading 22+ years.
£109.85 against a comparison-group median of £191.10 (-43%).
Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.
This test belongs to our DNA and methylation test comparison group. See how it stacks up against equivalent tests from other providers.
Ties for the deepest gene count among Stride's DNA panels
A cheek-swab DNA test covering 110 genes across methylation, nutrition, fitness, sleep, stress and skin. Suits people wanting Stride's fullest standalone DNA panel without the supplement bundle.
Priciest of Stride's DNA and methylation panels
A bundle combining Stride's 110-gene Optimal DNA & Methylation test with three months' supply of its methylated B-vitamin supplement. Suits people who want the deepest methylation panel plus an ongoing supplement in one purchase.
Middle of Stride's three DNA tiers on price and gene count
A cheek-swab DNA test analysing 52 genes across methylation and nutrient metabolism, showing how your body processes folate, B vitamins and dietary fat. Suited to people wanting more than a basic methylation panel without paying for the full 110-gene version.
Ties for the deepest gene count among Stride's DNA panels
A cheek-swab DNA test covering 110 genes across methylation, nutrition, fitness, sleep, stress and skin. Suits people wanting Stride's fullest standalone DNA panel without the supplement bundle.
Priciest of Stride's DNA and methylation panels
A bundle combining Stride's 110-gene Optimal DNA & Methylation test with three months' supply of its methylated B-vitamin supplement. Suits people who want the deepest methylation panel plus an ongoing supplement in one purchase.
Middle of Stride's three DNA tiers on price and gene count
A cheek-swab DNA test analysing 52 genes across methylation and nutrient metabolism, showing how your body processes folate, B vitamins and dietary fat. Suited to people wanting more than a basic methylation panel without paying for the full 110-gene version.
