Advanced DNA & Methylation Test

The five cycles in full, plus 24 reports on how you process food. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
Sample
Swab
Collection
At-home cheek swab, posted to the lab
Results in
10 days
Biomarkers
52
Doctor reviewed
No
Tests for
  • ADNOS3
  • BHMT
  • CBS (C699T)
  • COMT
  • DHFR
  • FUT2
  • GSS
  • MAOA
  • MAOB
  • MTHFD1
  • MTHFR (A1298C)
  • MTHFR (C677T)
  • +48 more

Test specifications

Provider
Stride
Sample type
swab
Collection method
at-home cheek swab, posted to the lab
Turnaround time
10 days
Biomarkers tested
52
At-home test
Yes
Doctor reviewed
No
Gender focus
Both

What's tested

60 biomarkers as listed by Stride.

Methylation

  • ADNOS3
  • BHMT
  • CBS (C699T)
  • COMT
  • DHFR
  • FUT2
  • GSS
  • MAOA
  • MAOB
  • MTHFD1
  • MTHFR (A1298C)
  • MTHFR (C677T)
  • MTR
  • MTRR
  • PEMT
  • SOD2ORA2A
  • TCN2
  • VDR

Nutrition

  • ACE
  • ADH1C
  • ADRB2
  • AGT
  • ALDOB
  • APOA2
  • APOA5
  • APOC3
  • APOE
  • BCMO1
  • BCO1
  • CAT
  • CBS
  • CETP
  • CLOCK
  • CYP1A2
  • CYP4F2
  • EPHX1
  • FABP2
  • FTO
  • GPX1
  • GSTT1
  • HFE
  • HLA DQ2/DQ8
  • IL6
  • INSIG
  • LCT/MCM6
  • LEPR
  • LIPC
  • LPL
  • MC4R
  • NBPF3
  • PLIN
  • PPARG
  • SLC23A1
  • SOD2
  • TCF7L2
  • TF
  • TFR2
  • TMPRSS6
  • TNF
  • ZPR1

About this test

Advanced - 52 Genes: The five cycles in full, plus 24 reports on how you process food.

The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT. Choose from three levels, then compare what each one covers below.

  • 1:1 expert consultation included with every level
  • Simple at-home cheek swab, results in 10 working days
  • Analysed at accredited specialist laboratories

Every level reads your core methylation pathways - including MTHFR and COMT - and includes a 1:1 expert consultation. Each step up widens the picture: Advanced adds nutrition and metabolism, Optimal adds fitness, sleep, stress and skin.

Description provided by Stride.

Our editorial score

Compare Health Test Score
Editorial confidence: 10.0/10

Score breakdown

  • Clarity and UX 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical Depth 7.5/10

    52 biomarkers against a median of 81 across the 4 tests in its comparison group.

  • Collection Convenience 6.0/10

    Can be done at home; results in around 10 days.

  • Price Value 7.1/10

    £174.85 against a comparison-group median of £191.10 (-9%).

  • Results and Follow-up 3.0/10

    Results are not doctor-reviewed as standard.

  • Trust Signals 7.5/10

    Trustpilot 4.7 from 148 reviews; accredited lab (UKAS accredited labs); trading 22+ years.

Compare with similar tests

This test belongs to our DNA and methylation test comparison group. See how it stacks up against equivalent tests from other providers.

View all →

Optimal DNA & Methylation Test

Methylation and nutrition in full, plus sleep, stress, skin and fitness. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
7.5 / 10 Best for broad methylation genetics

Methylation Stack

Optimal DNA & methylation test including 46 reports, plus 3 months' supply of MS-01, our methylated B vitamin complex. Unlock your methylation blueprint + daily support.

  • At-home test
7.0 / 10 Best for testing plus support bundle

Core DNA & Methylation Test

All five methylation cycles. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
6.9 / 10