Methylation Stack

Optimal DNA & methylation test including 46 reports, plus 3 months' supply of MS-01, our methylated B vitamin complex. Unlock your methylation blueprint + daily support.

  • At-home test
Sample
Swab
Collection
At-home cheek swab, posted to the lab
Results in
10 days
Biomarkers
110
Doctor reviewed
No
Tests for
  • ADNOS3
  • BHMT
  • CBS (C699T)
  • COMT
  • DHFR
  • FUT2
  • GSS
  • MAOA
  • MAOB
  • MTHFD1
  • MTHFR (A1298C)
  • MTHFR (C677T)
  • +48 more

Test specifications

Provider
Stride
Sample type
swab
Collection method
at-home cheek swab, posted to the lab
Turnaround time
10 days
Biomarkers tested
110
At-home test
Yes
Doctor reviewed
No
Report type
genetic-report
Gender focus
Both

What's tested

60 biomarkers as listed by Stride, of 110 in total.

Methylation

  • ADNOS3
  • BHMT
  • CBS (C699T)
  • COMT
  • DHFR
  • FUT2
  • GSS
  • MAOA
  • MAOB
  • MTHFD1
  • MTHFR (A1298C)
  • MTHFR (C677T)
  • MTR
  • MTRR
  • PEMT
  • SOD2ORA2A
  • TCN2
  • VDR

Nutrition

  • ACE
  • ADH1C
  • ADRB2
  • AGT
  • ALDOB
  • APOA2
  • APOA5
  • APOC3
  • APOE
  • BCMO1
  • BCO1
  • CAT
  • CBS
  • CETP
  • CLOCK
  • CYP1A2
  • CYP4F2
  • EPHX1
  • FABP2
  • FTO
  • GPX1
  • GSTT1
  • HFE
  • HLA DQ2/DQ8
  • IL6
  • INSIG
  • LCT/MCM6
  • LEPR
  • LIPC
  • LPL
  • MC4R
  • NBPF3
  • PLIN
  • PPARG
  • SLC23A1
  • SOD2
  • TCF7L2
  • TF
  • TFR2
  • TMPRSS6
  • TNF
  • ZPR1

About this test

About this test

Stride's Methylation Stack combines genetic methylation testing with an ongoing support product approach. It is designed for users who do not just want a report, but also want an immediate framework for acting on what the test suggests.

Who is this test for?

This option is best for users who want a more guided methylation experience, especially those who prefer a combined testing-and-support package rather than a standalone report.

How the test works

You complete the at-home genetic testing workflow, receive methylation-focused insights, and pair them with the bundled support products intended to help you act on the findings.

Pros & cons

Pros

  • Combines testing with a support bundle
  • Stronger action-orientation than test-only products
  • Good fit for users who want a guided next step
  • At-home workflow remains simple

Cons

  • Bundle format may be more than some users need
  • Less clean for users who only want a standalone report
  • Supplement suitability still needs personal judgement

Our editorial score

Compare Health Test Score Best for testing plus support bundle
Editorial confidence: 10.0/10

Score breakdown

  • Clarity and UX 10.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type, what the report contains.

  • Clinical Depth 9.8/10

    110 biomarkers against a median of 81 across the 4 tests in its comparison group.

  • Collection Convenience 6.0/10

    Can be done at home; results in around 10 days.

  • Price Value 3.3/10

    £278.85 against a comparison-group median of £191.10 (+46%).

  • Results and Follow-up 3.5/10

    Results are not doctor-reviewed as standard; genetic-report report.

  • Trust Signals 7.5/10

    Trustpilot 4.7 from 148 reviews; accredited lab (UKAS accredited labs); trading 22+ years.

Compare with similar tests

This test belongs to our DNA and methylation test comparison group. See how it stacks up against equivalent tests from other providers.

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Optimal DNA & Methylation Test

Methylation and nutrition in full, plus sleep, stress, skin and fitness. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
7.5 / 10 Best for broad methylation genetics

Advanced DNA & Methylation Test

The five cycles in full, plus 24 reports on how you process food. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
7.0 / 10

Core DNA & Methylation Test

All five methylation cycles. The Stride DNA & Methylation Test shows how efficiently your body methylates and uses key nutrients like folate and other B vitamins, with insight into genes such as MTHFR, MTR, MAOA and COMT.

  • At-home test
6.9 / 10