Randox's most extensive health panel, combining blood and urine testing with gut microbiome, food sensitivity and DNA analysis across 443 markers, plus a GP consultation.
60 biomarkers as listed by Randox Health, of 443 in total.
Signature combines a venous blood draw with an additional sample to cover 443 biomarkers, spanning areas such as heart health, cholesterol, diabetes and blood sugar, full blood count, kidney and liver function, thyroid function and antibodies, hormones, autoimmune markers, Epstein-Barr virus markers, gut bacterial composition, and vitamin D. The provider states it combines blood and urine testing with gut microbiome, food sensitivity, and nutritional and lifestyle DNA analysis, and includes a private GP consultation afterwards to go through the results and plan next steps.
Against its comparison group, Signature is priced far above every peer: the group median is £407.50, and even the next most expensive option, Stride's 180-marker Vital Duo at £460.85, costs a fraction of Signature's £2,112. In return, Signature tests roughly 2.5 times as many markers as Vital Duo. Within Randox's own range, Signature also differs from RanChip Insight 360 (£495, 160 markers) chiefly by including a doctor consultation, which RanChip does not.
The scores show this trade-off clearly. Clinical depth is the maximum score, since 443 biomarkers is far above the 82.5 median for the group. Value for money is low given the price gap versus peers. Results and follow-up scores reasonably well because a doctor consultation is included. Collection convenience is limited by the clinic visit, additional sample and multi-day wait, even though results come back within 4 working days.
This suits people who want the deepest panel Randox offers and are prepared to pay a substantial premium for it, along with a private GP consultation to discuss the results. For most people wanting a broad health check, cheaper options in the same comparison group cover 50 to 180 markers for a fraction of the price, and Randox's own RanChip Insight 360 covers 160 markers for £495 without the GP consultation.
You attend a Randox Health clinic for a venous blood draw plus an additional sample covering the gut microbiome, food sensitivity and DNA components. Results are available within 4 working days, after which you have a private GP consultation to go through them.
Signature tests 443 biomarkers by combining blood and urine analysis with gut microbiome, food sensitivity and DNA testing, and includes a private GP consultation to talk through the results. At £2,112 it costs roughly five times the £407.50 median for its comparison group, though it is also by far the deepest panel in that group. Collection needs a clinic visit plus an additional sample.
The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.
443 biomarkers against a median of 82.5 across the 10 tests in its comparison group.
Requires a venous draw at a clinic; results in around 4 days, slower than similar tests.
Results are reviewed by a doctor; a consultation is included in the price; the provider does not describe the report format.
Trustpilot 4.6 from 29,705 reviews; accredited lab (UKAS ISO 15189 (Randox Clinical Laboratory Services, lab 9329)); CQC registered.
£2,112.00 against a comparison-group median of £407.50 (+418%).
Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.
This test belongs to our Ultimate health check (over 50 markers) comparison group. See how it stacks up against equivalent tests from other providers.
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