Signature

One of our most advanced and comprehensive health assessments, designed to provide a deeper understanding of your health while helping you make more informed decisions for the future.

  • Doctor reviewed
Sample
Mixed
Collection
Venous draw at clinic plus additional sample
Results in
4 days
Biomarkers
443
Doctor reviewed
Yes
Tests for
  • IgE
  • Archael Composition
  • Anti-CCP
  • Anti-Nuclear Antibodies (ANA)
  • Anti-Tissue Transglutaminase Antibodies
  • Rheumatoid factor
  • Gastric parietal cell antibodies
  • Intrinsic factor antibodies
  • Bacteria that breakdown fibre
  • Bacteria with probiotic properties
  • Butyric acid producing bacteria
  • Hydrogen Sulphide producing Bacteria
  • +48 more

Test specifications

Sample type
mixed
Collection method
venous draw at clinic plus additional sample
Turnaround time
4 days
Biomarkers tested
443
At-home test
No
Doctor reviewed
Yes
Gender focus
Both

What's tested

60 biomarkers as listed by Randox Health, of 443 in total.

Allergy Evaluation

  • IgE

Archael Composition

  • Archael Composition

Autoimmune

  • Anti-CCP
  • Anti-Nuclear Antibodies (ANA)
  • Anti-Tissue Transglutaminase Antibodies
  • Rheumatoid factor

Autoimmunity

  • Gastric parietal cell antibodies
  • Intrinsic factor antibodies

Bacterial Composition

  • Bacteria that breakdown fibre
  • Bacteria with probiotic properties
  • Butyric acid producing bacteria
  • Hydrogen Sulphide producing Bacteria
  • Microbiome weight gain conditions
  • Pathogenic bacteria
  • Presence of Oxalate-degrading Bacteria
  • The Firmicutes/Bacteroidetes (F/B) ratio

Bone Health

  • Calcium (adjusted)
  • Parathyroid Hormone (PTH)
  • Phosphate

Cholesterol status

  • Apolipoprotein B

Clotting status

  • Platelet count

Diabetes

  • Fructosamine
  • Glucose
  • HbA1c
  • Insulin

Diabetes Health

  • C Peptide
  • Non-Esterified Fatty Acids

Digestive Health

  • H.Pylori

Epstein-Barr Virus

  • Epstein-Barr Antibodies
  • Epstein-Barr Nuclear Antigen IgG
  • Epstein-Barr Viral Capsid Antigen IgG
  • Epstein-Barr Viral Capsid Antigen IgM

Female Hormone

  • Sex-hormone Binding Globulin (SHBG)

Full Blood Count

  • Basophil Count
  • Eosinophil Count
  • Lymphocyte Count
  • Mean cell haemoglobin (MCH)
  • Mean Cell Haemoglobin Concentration (MCHC)
  • Monocyte Count
  • Neutrophil Count
  • Red blood cell count
  • Red Blood Cell Mean Volume (MCV)
  • White blood cell count

Heart Health

  • Apolipoprotein A-I
  • Apolipoprotein B / A-I Ratio

Hormones

  • Free androgen index
  • Oestradiol
  • Progesterone
  • Prolactin
  • Testosterone

Kidney health

  • Microalbumin : creatinine ratio

Liver Function

  • Alkaline Phosphatase (ALP)

Male Hormone

  • Follicle Stimulating Hormone (FSH)
  • Luteinising Hormone

Red blood cells

  • Haematocrit
  • Haemoglobin

Thyroid Health

  • Anti-Thyroglobulin Antibody (Anti-Tg)
  • Anti-Thyroid Peroxidase Antibody (Anti-TPO)

Viral Composition

  • Bacteriophages

Vitamins

  • Vitamin D

About this test

One of our most advanced and comprehensive health assessments, designed to provide a deeper understanding of your health while helping you make more informed decisions for the future. Measuring over 350 data points, Signature combines advanced blood and urine testing with Gut Microbiome, Food Sensitivity and Nutritional & Lifestyle DNA analysis to deliver a truly personalised view of your health. You'll receive a detailed personalised health report alongside a private GP consultation to help you understand your results, discuss any areas of concern and plan your next steps with confidence. With the option of repeat testing after 6 months, you can track progress over time, monitor important health trends and gain greater visibility into how your health is changing-helping you stay proactive and in control of your long-term wellbeing.

Understanding your health isn't just about identifying issues today-it's about gaining the knowledge and insights needed to make informed decisions for the future. Signature is designed to provide a detailed view of your health across multiple systems of the body, helping you establish a comprehensive baseline and uncover insights that may not be apparent through routine healthcare alone. Combining advanced biomarker analysis, genetic insights and personalised reporting, it offers a deeper understanding of the factors shaping your health and wellbeing. With optional repeat testing after 6 months, you can track meaningful changes over time, monitor progress and take a more informed, proactive approach to your long-term health and longevity.

  • Remote GP consultations
  • Up to 350 data points linked to key health areas
  • Results within 4 working days
  • Optional repeat testing every 6 months to track changes, monitor progress and stay ahead of potential issues

Description provided by Randox Health.

Our editorial score

Compare Health Test Score
Editorial confidence: 10.0/10

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 10.0/10

    443 biomarkers against a median of 82.5 across the 10 tests in its comparison group.

  • Collection convenience 4.0/10

    Requires a venous draw at a clinic; results within 5 days.

  • Results and follow-up 7.5/10

    Results are reviewed by a doctor.

  • Trust signals 9.0/10

    Trustpilot 4.6 from 29,705 reviews; accredited lab (UKAS ISO 15189 (Randox Clinical Laboratory Services, lab 9329)); CQC registered.

  • Value for money 2.0/10

    £2,112.00 against a comparison-group median of £407.50 (+418%).

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