Better2Know Inflammation & autoimmunity

Extractable Nuclear Antigen Panel

A blood test for extractable nuclear antigen autoantibodies, markers associated with autoimmune conditions such as lupus and Sjögren's syndrome. It suits people with relevant symptoms or a prior abnormal ANA result.

Sample
Blood
Collection
Venous draw at clinic
Results in
2 days
Biomarkers
1
Tests for
  • Extractable Nuclear Antigen Panel

Test specifications

Provider
Better2Know
Sample type
blood
Collection method
venous draw at clinic
Turnaround time
2 days
Biomarkers tested
1
At-home test
No
Doctor reviewed
No
Gender focus
Both

What's tested

1 biomarker as listed by Better2Know.

  • Extractable Nuclear Antigen Panel

About this test

The extractable nuclear antigen panel checks for a group of autoantibodies that target proteins inside the cell nucleus. These antibodies are commonly used to assess autoimmune conditions such as lupus, Sjögren's syndrome and mixed connective tissue disease, and this kind of test is often used alongside, or after, an antinuclear antibody (ANA) result.

Against the other inflammation and autoimmunity tests we track, this panel scores in the lower range for clinical depth, since it covers one marker group rather than a wider antibody or inflammation panel. At £145 it costs noticeably more than the typical price for similarly sized tests in this category, which is reflected in a low value for money score. There is no comparison group of directly equivalent named tests on the site yet, so we cannot point to a specific cheaper alternative.

The clarity score is high because the listing sets out the sample type, collection method and turnaround clearly. The lower score for results and follow-up reflects that results are not reviewed by a doctor as standard, so you should plan to discuss any findings with your own GP or specialist.

Who is it for?

This test may suit people with symptoms suggestive of an autoimmune condition, such as persistent joint or muscle pain, fatigue, rashes, or dry eyes and mouth, or people who have already had an abnormal ANA result and want the extractable nuclear antigen antibodies checked. It can also be used to monitor known autoimmune disease activity.

Because there is no comparison group of similar tests in the data, we cannot say whether a cheaper or broader autoimmune panel is available elsewhere. It may be worth discussing initial autoimmune investigations with your GP before booking a specific panel like this privately. As results are not reviewed by a doctor as standard, you should take any findings to your GP or specialist.

How it works

This test uses a single venous blood sample, taken at a Better2Know clinic. Once the sample reaches the laboratory, it is analysed for extractable nuclear antigen autoantibodies, with results typically available within two days. Better2Know arranges a doctor consultation if your result is positive, though results are not reviewed by a doctor as standard otherwise.

Pros & cons

Pros

  • Checks for autoantibodies linked to autoimmune conditions such as lupus and Sjögren's syndrome in one blood draw.
  • Results are typically available within two days.
  • The listing clearly states the sample type and collection method.

Cons

  • Covers a single marker group rather than a wider inflammation or antibody panel.
  • At £145, priced above the typical cost for similarly sized inflammation tests.
  • No standard doctor review of the results.
  • Only available via an in-clinic venous draw, not as an at-home kit.

Our editorial score

Compare Health Test Score Single-marker autoimmune test priced above category norm
Editorial confidence: 9.0/10

This £145 test looks for a single group of autoantibodies linked to autoimmune conditions such as lupus and Sjögren's syndrome. It costs more than the typical price for similarly sized inflammation and autoimmunity tests we track, despite covering only one marker group. There is no doctor review of the results as standard, so any positive finding needs following up with your GP.

Score breakdown

  • Clarity and documentation 9.0/10

    The listing publishes a detailed description, the full biomarker list, a stated turnaround, clear collection options, the sample type; it does not state what the report looks like.

  • Clinical depth 6.4/10

    1 biomarkers, placing it in the 32nd percentile of inflammation tests we track.

  • Collection convenience 5.0/10

    Requires a venous draw at a clinic; results in around 2 days, well ahead of the inflammation norm of 4.

  • Results and follow-up 3.0/10

    Results are not doctor-reviewed and no consultation is included; the provider does not describe the report format.

  • Trust signals 6.5/10

    Trustpilot 4.2 from 775 reviews; CQC registered; trading 18+ years.

  • Value for money 3.3/10

    £145.00 against a median of £88.63 for the 26 similarly sized inflammation tests we track (+64%).

Calculated 13 September 2026 from the facts we hold about this test and provider, using our published scoring formula. Scores are not hand-edited.

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